Acute cerebellar ataxia

Infectious diseases

General description

Acute cerebellar ataxia represents the predominant cause of ataxia in children, accounting for 40% of all pediatric ataxia cases. This condition, known for its favorable prognosis, often follows an infection or immunization. Varicella-zoster virus is identified as a leading cause of the preceding infection. Additionally, mumps virus, enteroviruses (such as ECHO and coxsackie), measles virus, HSV-1, parvovirus, and rotavirus have also been reported as causative agents. Among these, mumps ranks as the second most common preceding infection leading to acute cerebellar ataxia, following varicella.

Radiographic features

Imaging studies reveal bilateral diffuse cerebellar swellings and T2WI/FLAIR hyperintensities. Leptomeningeal contrast enhancement in the cerebellar pia mater is observed. Occasionally, diffusion restriction is observed at the splenium of the corpus callosum.

Cerebellar lesion

  • Cerebellum
Symmetric
Bilateral
Diffuse
T2WI
Hyperintensity
FLAIR
Hyperintensity
Symmetric
Bilateral
Morphology
Enlargement / swelling

Leptomeningitis

  • Leptomenix
    Cerebellar leptomenix
Symmetric
Bilateral
Morphology
Thickening
CE T1WI
Enhancement
CE FLAIR
Enhancement

Corpus callosal lesion

  • Corpus callosum
    Splenium
Symmetric
Bilateral
DWI
Hyperintensity
ADC
Hypointensity