Brain abscess

Infectious diseases

General description

Brain abscesses form when an inflamed area of the brain undergoes necrosis and is surrounded by a capsule of glial cells and fibroblasts. Edema around the abscess, as well as the abscess itself, can increase intracranial pressure.

Abscess

  • Anywhere in the brain
Homogeneous
Central
T1WI
Hypointensity
T2WI
Hyperintensity
DWI
Hyperintensity
ADC
Hypointensity
Peripheral
T1WI
Hyperintensity
Isointensity
T2WI
Hypointensity
SWI
Hypointensity
Ring shaped
CE T1WI
Enhancement
Inner peripheral
SWI
Hyperintensity

Brain abscess is characterized by peripherally distributing circumscribed encapsulation with T2WI hypointensity and T1WI iso-hyperintensity, attributed to the paramagnetic effect of free radicals produced by activated macrophages.

High concentrations of cell decay products by macrophages show homogeneous diffusion restriction in the central area.

SWI shows circumferential hypointensity along abscess wall. SWI also shows a region of high intensity just inside the peripheral low signal, called dual rim sign.