Hemolytic uremic syndrome (HUS)
General description
Hemolytic uremic syndrome (HUS) is a rare condition that typically occurs when an infection in the digestive system produces toxic substances that destroy red blood cells. This leads to kidney injury and sometimes kidney failure. HUS is most commonly associated with an infection by certain strains of E. coli bacteria, particularly E. coli O157:H7, which is often found in contaminated food or water.
The symptoms of HUS may include:
- Bloody diarrhea
- Abdominal pain
- Fever
- Vomiting
- Pale skin tone
- Small, unexplained bruises or bleeding
- Fatigue
- Decreased frequency of urination
References
- Mansour, Moustafa A., et al. "Hemolytic uremic syndrome with central nervous system manifestations, a case report and literature review." Radiology Case Reports 18.6 (2023): 2268-2273.
Lentiform fork sign
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Putamen
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Globus pallidus
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Internal capsulePosterior limb
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External capsule
The linear hyperintense signal seen on T2WI and FLAIR in the external capsule and the posterior limb of the internal capsule resembles the prong of a fork. The hyperintensity of the lentiform nuclei on T2WI and FLAIR is enclosed by this fork-like structure. Additionally, DWI may show restricted diffusion in the hyperintense region, along with a decreased ADC, which may suggest cytotoxic injury.
T2WI and FLAIR hyperintensity
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CerebrumCerebral white matter
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Thalamus
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Brainstem
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Cerebellum
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Corpus callosum