Human herpesvirus 6 encephalitis
Infectious diseases
General description
Human Herpesvirus 6 (HHV-6) encephalitis is primarily known for its association with roseola infantum, a common childhood illness. Recently, with the increase in organ transplant procedures, the reactivation of HHV-6 following immunosuppression has become a significant concern. As a result, HHV-6 is now recognized as one of the causative organisms of post-transplant encephalitis, highlighting the importance of monitoring and managing this virus in immunocompromised patients.
Limbic encephalitis
Non-SOL
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CerebrumTemporal lobeHippocampus
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CerebrumTemporal lobeAmygdala
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CerebrumInsula
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CerebrumFrontal lobe
HHV-6 typically targets the limbic system, affecting areas such as the hippocampus, amygdala, and insular cortex. The inferior frontal lobe can also be involved, illustrating the virus's propensity for critical areas involved in memory, emotion, and behavior.