Posterior cortical atrophy (PCA)
General description
Posterior cortical atrophy (PCA), also known as Benson syndrome, is a rare neurodegenerative disease that primarily affects the posterior regions of the brain, including the parietal, posterior temporal, and occipital lobes. It typically develops in individuals in their 60s and 70s and is most commonly caused by Alzheimer's disease.
The condition is characterized by progressive impairments in visuospatial and visuoperceptual abilities, leading to difficulties in recognizing visual information and spatial relationships. Additionally, patients experience apraxia, which affects motor planning and execution, as well as literacy deficits, including difficulties with reading and writing.
Atrophy
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CerebrumParietal lobe
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CerebrumOccipital lobe
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CerebrumTemporal lobe
The findings indicate a pattern of atrophy primarily affecting the occipital, parietal, and posterior temporal lobes. This atrophy is present on both sides but is more pronounced on the right. The hippocampi appear relatively normal.